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HPV (Human Papillomavirus) Genotyping

Los Angeles - United States | General information | Popularity - 0/10
We all have heard that Human Papillomavirus (HPV) is almost always linked to cervical cancer. What do we actually know thus far regarding this statement? I have had patients coming into my clinic with genital warts, in such panic and anxious mode, asking me “Doctor does this mean i have cervical cancer?”
What is HPV? HPV is the collective term for a group of over 100 different viruses. This virus is the most common viral infection of the reproductive tract. Most sexually active women and men will be infected at some point in their lives and some may be repeatedly infected. HPV is sexually transmitted, but penetrative sex is not required for transmission. Skin-to-skin genital contact is a well-recognized mode of transmission.  HPV Vaccination
HPVs are attracted to certain cells called squamous epithelial cells. These cells are found on the surface of the skin and on moist surfaces (called mucosal surfaces) like:
·         The trachea (windpipe) and bronchi (smaller breathing tubes branching off the trachea)
·         The inner lining of the nose, mouth, and throat
·         The vagina, cervix, vulva (area around the outside of the vagina), and anus
·         The inner foreskin and urethra of the penis
·         The inner eyelids
 You DO NOT get HPV from:
·         Toilet seats
·         Hugging or holding hands
·         Swimming in pools or hot tubs
·         Sharing food or utensils
·         Being unclean
Low risk vs High risk HPV
Low-risk mucosal (genital) HPV types: this type tends to cause warts and rarely cause cancer are called low-risk types. Low-risk genital HPV infection can cause warts (usually resembles cauliflower) on or around the genitals and anus of both men and women. In women, warts may appear in areas that aren’t always noticed, such as the cervix and vagina. HPV Vaccine
High-risk mucosal (genital) HPV types: these are the types of viruses that are usually linked to cancer thus called high-risk types. These types have been linked to certain cancers in both men and women.
HPV Testing
Difference between PAP SMEAR and HPV testing:
A Pap test detects cell changes or abnormal cells in the cervix. These abnormal cells may be pre-cancer or cancer, but they may also be other things, too. Cells are lightly scraped or brushed off the cervix. The Pap test is a very good test for finding cancer cells and cells that might become cancer.
As we all know, HPV is closely linked to cervical cancer. The HPV test checks for the virus, not cell changes. There is an option called co-testing. In this co- testing, Pap smear and HPV testing will be done together. This is by far the most preferred way to find early cervical cancers or pre-cancers in women 30 and older.
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